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1

Psychological distress of patients suffering from restless legs syndrome: a cross-sectional study

Hanna Scholz, Heike Benes, Svenja Happe, Juergen Bengel, Ralf Kohnen, Magdolna Hornyak

Journal:

Health and Quality of Life Outcomes

Year:

2011

Language:

english

File:

PDF, 199 KB

english, 2011

2

Prolonged release oxycodone–naloxone for treatment of severe restless legs syndrome after failure of previous treatment: a double-blind, randomised, placebo-controlled trial with an open-label extension

Trenkwalder, Claudia, Beneš, Heike, Grote, Ludger, García-Borreguero, Diego, Högl, Birgit, Hopp, Michael, Bosse, Björn, Oksche, Alexander, Reimer, Karen, Winkelmann, Juliane, Allen, Richard P, Kohnen,

Journal:

The Lancet Neurology

Year:

2013

Language:

english

File:

PDF, 239 KB

english, 2013

3

Definition of restless legs syndrome, how to diagnose it, and how to differentiate it from RLS mimics

Heike Benes, Arthur S. Walters, Richard P. Allen, Wayne A. Hening, Ralf Kohnen

Journal:

Movement Disorders

Year:

2007

Language:

english

File:

PDF, 80 KB

english, 2007

4

Relation of the International Restless Legs Syndrome Study Group rating scale with the Clinical Global Impression severity scale, the restless legs syndrome 6-item questionnaire, and the restless legs syndrome-quality of life questionnaire

Allen, Richard, Oertel, Wolfgang, Walters, Arthur, Benes, Heike, Schollmayer, Erwin, Grieger, Frank, Moran, Kimberly, Kohnen, Ralf

Journal:

Year:

2013

Language:

english

File:

PDF, 533 KB

english, 2013

5

Cabergoline compared to levodopa in the treatment of patients with severe restless legs syndrome: Results from a multi-center, randomized, active controlled trial

Claudia Trenkwalder, Heike Benes, Ludger Grote, Svenja Happe, Birgit Högl, Johannes Mathis, Gerda M. Saletu-Zyhlarz, Ralf Kohnen

Journal:

Movement Disorders

Year:

2007

Language:

english

File:

PDF, 128 KB

english, 2007

6

Clinical trials in restless legs syndrome—Recommendations of the European RLS Study Group (EURLSSG)

Claudia Trenkwalder, Ralf Kohnen, Richard P. Allen, Heike Benes̆, Luigi Ferini-Strambi, Diego Garcia-Borreguero, Georgios M. Hadjigeorgiou, Svenja Happe, Birgit Högl, Magdolna Hornyak, Christine Klein

Journal:

Movement Disorders

Year:

2007

Language:

english

File:

PDF, 90 KB

english, 2007

7

State of the art in restless legs syndrome therapy: Practice recommendations for treating restless legs syndrome

Wolfgang H. Oertel, Claudia Trenkwalder, Marco Zucconi, Heike Benes, Diego Garcia Borreguero, Claudio Bassetti, Markku Partinen, Luigi Ferini-Strambi, Karin Stiasny-Kolster

Journal:

Movement Disorders

Year:

2007

Language:

english

File:

PDF, 115 KB

english, 2007

8

Assessment of restless legs syndrome—Methodological approaches for use in practice and clinical trials

Ralf Kohnen, Richard P. Allen, Heike Benes, Diego Garcia-Borreguero, Wayne A. Hening, Karin Stiasny-Kolster, Marco Zucconi

Journal:

Movement Disorders

Year:

2007

Language:

english

File:

PDF, 93 KB

english, 2007

9

Augmentation as a treatment complication of restless legs syndrome: Concept and management

Diego García-Borreguero, Richard P. Allen, Heike Benes, Christopher Earley, Svenja Happe, Birgit Högl, Ralf Kohnen, Walter Paulus, David Rye, Juliane Winkelmann

Journal:

Movement Disorders

Year:

2007

Language:

english

File:

PDF, 184 KB

english, 2007

10

Algorithms for the diagnosis and treatment of restless legs syndrome in primary care

Diego Garcia-Borreguero, Paul Stillman, Heike Benes, Heiner Buschmann, K Ray Chaudhuri, Victor M Gonzalez Rodríguez, Birgit Högl, Ralf Kohnen, Giorgio Carlo Monti, Karin Stiasny-Kolster, Claudia Trenk

Journal:

Year:

2011

Language:

english

File:

PDF, 1.41 MB

english, 2011

11

Ropinirole improves depressive symptoms and restless legs syndrome severity in RLS patients: a multicentre, randomized, placebo-controlled study

Heike Benes, Wolfgang Mattern, Ines Peglau, Tillmann Dreykluft, Lars Bergmann, Corinna Hansen, Ralf Kohnen, Norbert Banik, S. W. Schoen, Magdolna Hornyak

Journal:

Journal of Neurology

Year:

2011

Language:

english

File:

PDF, 412 KB

english, 2011

12

Nocturnal serum leptin values in chronic primary insomnia: A preliminary report

Svenja Happe, Heike Beneš, Magdolna Hornyak, Sylvia Kotterba, Geert Mayer, Karin Stiasny-Kolster, Mitglieder der Arbeitsgemeinschaft „Motorik und Schlaf‘‘ der Deutschen Gesellschaft für Schlafforschun

Journal:

Somnologie - Schlafforschung und Schlafmedizin

Year:

2006

File:

PDF, 70 KB

2006

13

Transcriptional complexes engaged by apo-estrogen receptor-α isoforms have divergent outcomes

Métivier, Raphaël, Penot, Graziella, Carmouche, Richard P, Hübner, Michael R, Reid, George, Denger, Stefanie, Manu, Dominique, Brand, Heike, Koš, Martin, Benes, Vladimir

Journal:

The EMBO Journal

Year:

2004

Language:

english

File:

PDF, 443 KB

english, 2004

14

Multiple mechanisms induce transcriptional silencing of a subset of genes, including oestrogen receptor α, in response to deacetylase inhibition by valproic acid and trichostatin A

Reid, George, Métivier, Raphaël, Lin, Chin-Yo, Denger, Stefanie, Ibberson, David, Ivacevic, Tomi, Brand, Heike, Benes, Vladimir, Liu, Edison T, Gannon, Frank

Journal:

Year:

2005

Language:

english

File:

PDF, 766 KB

english, 2005

15

Efficacy of rotigotine for treatment of moderate-to-severe restless legs syndrome: a randomised, double-blind, placebo-controlled trial

Claudia Trenkwalder, Heike Beneš, Werner Poewe, Wolfgang H Oertel, Diego Garcia-Borreguero, Al W de Weerd, Luigi Ferini-Strambi, Pasquale Montagna, Per Odin, Karin Stiasny-Kolster, Birgit Högl, K Ray

Journal:

The Lancet Neurology

Year:

2008

Language:

english

File:

PDF, 213 KB

english, 2008

16

Long-term safety and efficacy of rotigotine transdermal patch for moderate-to-severe idiopathic restless legs syndrome: a 5-year open-label extension study

Wolfgang Oertel, Claudia Trenkwalder, Heike Beneš, Luigi Ferini-Strambi, Birgit Högl, Werner Poewe, Karin Stiasny-Kolster, Andreas Fichtner, Erwin Schollmayer, Ralf Kohnen, Diego García-Borreguero

Journal:

The Lancet Neurology

Year:

2011

Language:

english

File:

PDF, 391 KB

english, 2011

17

Treatment of moderate to severe restless legs syndrome: 2-year safety and efficacy of rotigotine transdermal patch

Birgit Högl, Wolfgang H Oertel, Karin Stiasny-Kolster, Peter Geisler, Heike Beneš, Diego García-Borreguero, Claudia Trenkwalder, Werner Poewe, Erwin Schollmayer, Ralf Kohnen

Journal:

Year:

2010

Language:

english

File:

PDF, 552 KB

english, 2010

18

Transdermal lisuride: short-term efficacy and tolerability study in patients with severe restless legs syndrome

Journal:

Year:

2006

Language:

english

File:

PDF, 95 KB

english, 2006

19

Efficacy of rotigotine transdermal system in severe restless legs syndrome: A randomized, double-blind, placebo-controlled, six-week dose-finding trial in Europe

Wolfgang H. Oertel, Heike Benes, Diego Garcia-Borreguero, Peter Geisler, Birgit Högl, Bernd Saletu, Claudia Trenkwalder, Kenneth W. Sommerville, Erwin Schollmayer, Ralf Kohnen, Karin Stiasny-Kolster

Journal:

Year:

2008

Language:

english

File:

PDF, 392 KB

english, 2008

20

Augmentation in restless legs syndrome is associated with low ferritin

Claudia Trenkwalder, Birgit Högl, Heike Benes, Ralf Kohnen

Journal:

Year:

2008

Language:

english

File:

PDF, 81 KB

english, 2008

21

One year open-label safety and efficacy trial with rotigotine transdermal patch in moderate to severe idiopathic restless legs syndrome

Wolfgang H. Oertel, Heike Benes, Diego Garcia-Borreguero, Peter Geisler, Birgit Högl, Claudia Trenkwalder, Ingrid Tacken, Erwin Schollmayer, Ralf Kohnen, Karin Stiasny-Kolster

Journal:

Year:

2008

Language:

english

File:

PDF, 206 KB

english, 2008

22

Empirical evaluation of the accuracy of diagnostic criteria for Restless Legs Syndrome

Heike Beneš, Alexander von Eye, Ralf Kohnen

Journal:

Year:

2009

Language:

english

File:

PDF, 123 KB

english, 2009

23

Validation of an algorithm for the diagnosis of Restless Legs Syndrome: The Restless Legs Syndrome-Diagnostic Index (RLS-DI)

Heike Beneš, Ralf Kohnen

Journal:

Year:

2009

Language:

english

File:

PDF, 169 KB

english, 2009

24

Augmentation in the treatment of restless legs syndrome with transdermal rotigotine

Heike Beneš, Diego García-Borreguero, Luigi Ferini-Strambi, Erwin Schollmayer, Andreas Fichtner, Ralf Kohnen

Journal:

Year:

2012

Language:

english

File:

PDF, 192 KB

english, 2012

25

RELATIONSHIP BETWEEN CLINICALLY SIGNIFICANT AUGMENTATION OF RESTLESS LEGS SYNDROME (RLS) AND DOSAGE OF ROTIGOTINE TRANSDERMAL SYSTEM: POST HOC ANALYSIS OF A 5-YEAR PROSPECTIVE, MULTINATIONAL, OPEN-LABEL STUDY

Luigi Ferini Strambi, Ralf Kohnen, Heike Beneš, Birgit Högl, Wolfgang Oertel, Claudia Trenkwalder, Andreas Fichtner, Erwin Schollmayer, Diego García-Borreguero

Journal:

Year:

2011

Language:

english

File:

PDF, 65 KB

english, 2011

26

W-L-090 DISEASE-SPECIFIC QUALITY OF LIFE (QOL) IN RESTLESS LEGS SYNDROME (RLS): VALIDATION OF THE QOL-RLS QUESTIONNAIRE

Ralf Kohnen, Heike Beneŝ, Birgit Högl, Birgit Högl, Julia Hülsmann, Wolfgang Oertel, Karin Stiasny-Kolster, Claudia Trenkwalder

Journal:

Year:

2011

Language:

english

File:

PDF, 68 KB

english, 2011

27

W-L-101 RESULTS OF A GERMAN SURVEY OF SYMPTOMS AND MEDICATION USE IN PATIENTSWITH RESTLESS LEGS SYNDROME (RLS)

Heike Beneŝ, Nicole Reketat, Reinhard Berkels

Journal:

Year:

2011

Language:

english

File:

PDF, 65 KB

english, 2011

28

W-L-105 SYMPTOM SEVERITY RATING IN RESTLESS LEGS SYNDROME (RLS): VALIDATION OF THE RLS-6 SCALES

Ralf Kohnen, Heike Beneŝ, Birgit Högl, Julia Hülsmann, Wolfgang Oertel, Karin Stiasny-Kolster, Claudia Trenkwalder

Journal:

Year:

2011

Language:

english

File:

PDF, 84 KB

english, 2011

29

European guidelines on management of restless legs syndrome: report of a joint task force by the European Federation of Neurological Societies, the European Neurological Society and the European Sleep Research Society

Diego Garcia-Borreguero, Luigi Ferini-Strambi, Ralf Kohnen, Shaun O'Keeffe, Claudia Trenkwalder, Birgit Högl, Heike Benes, Poul Jennum, Markku Partinen, Danyal Fer, Pasquale Montagna, Claudio L. Basse

Journal:

European Journal of Neurology

Year:

2012

Language:

english

File:

PDF, 525 KB

english, 2012

30

Rotigotine transdermal patch in moderate to severe idiopathic restless legs syndrome: A randomized, placebo-controlled polysomnographic study

Wolfgang H. Oertel, Heike Beneš, Diego Garcia-Borreguero, Birgit Högl, Werner Poewe, Pasquale Montagna, Luigi Ferini-Strambi, Friederike Sixel-Döring, Claudia Trenkwalder, Markku Partinen, Bernd Salet

Journal:

Year:

2010

Language:

english

File:

PDF, 363 KB

english, 2010

31

Modafinil in the treatment of idiopathic hypersomnia without long sleep time-a randomized, double-blind, placebo-controlled study

Mayer, Geert, Benes, Heike, Young, Peter, Bitterlich, Marion, Rodenbeck, Andrea

Journal:

Journal of Sleep Research

Year:

2015

Language:

english

File:

PDF, 184 KB

english, 2015

32

Was gibt es Neues zum Restless-legs-Syndrom?

Journal:

Psycho - Psychiatrie · Neurologie · Psychotherapie

Year:

2004

Language:

german

File:

PDF, 181 KB

german, 2004

33

Transcriptome Profiling of Estrogen-Regulated Genes in Human Primary Osteoblasts Reveals an Osteoblast-Specific Regulation of the Insulin-Like Growth Factor Binding Protein 4 Gene

Denger, Stefanie, Bähr-Ivacevic, Tomi, Brand, Heike, Reid, George, Blake, Jonathon, Seifert, Martin, Lin, Chin-Yo, May, Klaus, Benes, Vladimir, Liu, Edison T., Gannon, Frank

Journal:

Molecular Endocrinology

Year:

2008

Language:

english

File:

PDF, 742 KB

english, 2008

34

Rotigotine in Hemodialysis-Associated Restless Legs Syndrome: A Randomized Controlled Trial

Dauvilliers, Yves, Benes, Heike, Partinen, Markku, Rauta, Virpi, Rifkin, Daniel, Dohin, Elisabeth, Goldammer, Nadine, Schollmayer, Erwin, Schröder, Hanna, Winkelman, John W.

Journal:

American Journal of Kidney Diseases

Year:

2016

Language:

english

File:

PDF, 437 KB

english, 2016

35

Rating of daytime and nighttime symptoms in RLS: validation of the RLS-6 scale of restless legs syndrome/Willis–Ekbom disease

Kohnen, Ralf, Martinez-Martin, Pablo, Benes, Heike, Trenkwalder, Claudia, Högl, Birgit, Dunkl, Elmar, Walters, Arthur S.

Journal:

Year:

2016

Language:

english

File:

PDF, 245 KB

english, 2016

36

Management of augmentation of restless legs syndrome with rotigotine: a 1-year observational study

Trenkwalder, Claudia, Canelo, Monica, Lang, Michael, Schroeder, Hanna, Kelling, Daniela, Berkels, Reinhard, Schollmayer, Erwin, Heidbrede, Tanja, Benes, Heike

Journal:

Year:

2015

Language:

english

File:

PDF, 397 KB

english, 2015

37

Review of Severity Rating Scales for Restless Legs Syndrome: Critique and Recommendations

Walters, Arthur S., Frauscher, Birgit, Allen, Richard, Benes, Heike, Chaudhuri, K. Ray, Garcia-Borreguero, Diego, Lee, Hochang B., Picchietti, Daniel L., Trenkwalder, Claudia, Martinez-Martin, Pablo,

Journal:

Movement Disorders Clinical Practice

Year:

2014

Language:

english

File:

PDF, 121 KB

english, 2014

38

Validation of the Kohnen Restless Legs Syndrome–Quality of Life instrument

Kohnen, Ralf, Martinez-Martin, Pablo, Benes, Heike, Trenkwalder, Claudia, Högl, Birgit, Dunkl, Elmar, Walters, Arthur S.

Journal:

Year:

2016

Language:

english

File:

PDF, 947 KB

english, 2016

39

Clinically relevant cut-off values for the parkinson's disease sleep scale-2 (PDSS-2): a validation study

Muntean, Maria-Lucia, Benes, Heike, Sixel-Döring, Friederike, Chaudhuri, Kallol Ray, Suzuki, Keisuke, Hirata, Koichi, Zimmermann, Johannes, Trenkwalder, Claudia

Journal:

Year:

2016

Language:

english

File:

PDF, 1.26 MB

english, 2016

40

Detection of Impaired Homologous Recombination Repair in NSCLC Cells and Tissues

Birkelbach, Moritz, Ferraiolo, Natalie, Gheorghiu, Liliana, Pfäffle, Heike N., Daly, Benedict, Ebright, Michael I., Spencer, Cheryl, O'Hara, Carl, Whetstine, Johnathan R., Benes, Cyril H., Sequist, Le

Journal:

Journal of Thoracic Oncology

Year:

2013

Language:

english

File:

PDF, 2.76 MB

english, 2013

41

Review of Quality of Life Instruments for the Restless Legs Syndrome/Willis-Ekbom Disease (RLS/WED): Critique and Recommendations

Walters, Arthur S., Frauscher, Birgit, Allen, Richard, Benes, Heike, Chaudhuri, K. Ray, Garcia-Borreguero, Diego, Lee, Hochang B., Picchietti, Daniel L., Trenkwalder, Claudia, Martinez-Martin, Pablo,

Journal:

Journal of Clinical Sleep Medicine

Year:

2014

Language:

english

File:

PDF, 300 KB

english, 2014

42

A randomized Phase 2 study to evaluate the orexin-2 receptor antagonist seltorexant in individuals with insomnia without psychiatric comorbidity

De Boer, Peter, Drevets, Wayne C, Rofael, Hany, van der Ark, Peter, Kent, Justine M, Kezic, Iva, Parapatics, Silvia, Dorffner, Georg, van Gerven, Joop, Beneš, Heike, Keicher, Christian, Jahn, Holger,

Journal:

Journal of Psychopharmacology

Year:

2018

Language:

english

File:

PDF, 527 KB

english, 2018

43

Functional Characterisation of the Maturation of the Blood-Brain Barrier in Larval Zebrafish

Fleming, Angeleen, Diekmann, Heike, Goldsmith, Paul, Del Bene, Filippo

Journal:

Year:

2013

Language:

english

File:

PDF, 2.13 MB

english, 2013

44

Rapid Onset of Action of Levodopa in Restless Legs Syndrome: A Double-Blind, Randomized, Multicenter, Crossover Trial

Beneš, Heike, Kurella, Brigitte, Kummer, Juergen, Kazenwadel, Joerg, Selzer, Roland, Kohnen, Ralf

Journal:

Year:

1999

Language:

english

File:

PDF, 105 KB

english, 1999

45

Effects of Solriamfetol on Quality of Life Measures From a 12-Week Phase 3 Randomized Trial

Weaver, Terri E, Drake, Christopher L, Benes, Heike, Stern, Thomas, Maynard, James, Thein, Stephen G., Andry, James M., Hudson, John D., Chen, Dan, Carter, Lawrence P., Bron, Morgan, Lee, Lawrence, Bl

Journal:

Annals of the American Thoracic Society

Year:

2020

File:

PDF, 366 KB

2020

46

Development and Validation of the Insomnia Daytime Symptoms and Impacts Questionnaire (IDSIQ)

Hudgens, Stacie, Phillips-Beyer, Andrea, Newton, Louise, Seboek Kinter, Dalma, Benes, Heike

Journal:

The Patient: Patient-Centered Outcomes Research

Year:

2020

File:

PDF, 1.29 MB

2020